Abberior 3D MINFLUX “super-resolution” microscope

The Scripps Core Microscopy Facility houses an Abberior 3D MINFLUX “super-resolution” microscope. This system, developed in the lab of Dr. Stefan Hell, provides molecular localization precision in fixed samples of approximately 2 nm in all 3 dimensions (X,Y,Z). The system may also be used to track single molecule movements with a temporal resolution as low as 100 µsec. The Scripps Research Core Microscopy Facility’s MINFLUX system was the first one to be installed in North America. The system is equipped with two MINFLUX Lasers (561 nm & 642 nm), adaptive optics, active sub nm accuracy sample stabilization in XYZ, 3D autofocus module, an Olympus IX83 microscope body, four confocal excitation lasers (405, 485, 561, and 640 nm), full auto-alignment, and 5 detection channels.